Mutation Deletion in DNA
By: Blake Noble
Deletion:
Deletion is a mutation in the chromosome sequence in DNA. Deletion happens when a molecule of DNA failed to be copied during the replication process.
Nucleotides are units of DNA that consists of deoxyribose (a sugar), phosphate group, and a nitrogen base.
Each molecule in the DNA has two strands. For example, in the original DNA strand there is cytosine, and on the complementary strand, there is Guanine. These both will pair together just like how Adenine pairs with Thymine. These are called base pairs. ex) A always pairs with T, and G always pairs with C. Same is applied in reverse.
An example of this mutation is depicted below.
As you can see each pair then create codons of three that each code for a certain Amino Acid. In the mutation of deletion, if one and/or more of the molecules (as stated before) fails to be paired in the replication process, it could potentially throw off the rest of the process and cause severe diseases.
Source of Reference & Pictures: http://study.com/academy/lesson/deletion-mutation-definition-examples-diseases.html
What kinds of diseases can it cause?
ReplyDeleteA deletion mutation can cause a wide variety of problems and most of them are fatal. Minor effects of this mutation can cause Cystic Fibrosis, Turner Syndrome, and many other countless syndromes that have dangerous long term effects.
ReplyDeleteSo G only applies with C and A only applies with T. Are there any exceptions?
ReplyDelete